Drew Barrymore and Adam Sander have great on-screen chemistry ... but have they ever hooked up off-screen? 

The stars of "Blended" sat down with "Chelsea Lately's" Chelsea Handler on Thursday where they talked about shooting the romantic comedy in South Africa and revealed if they have ever tried dating for real!

Check out the video above to see what they said!

People just love to watch Adam and Drew play a couple on the big screen -- from "The Wedding Singer," to "50 First Dates" and now in "Blended," the actors definitely make one adorable couple on film.

Did you notice how they held hands during the first part of the interview? So cute!

We're definitely looking forward to seeing the hilarious duo grace the silver screen again this weekend -- what do you think about Sandler and Barrymore's candid confession?

Sound off below and make sure to check out "Blended" when it hits theaters nationwide Friday!

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