"I always say that there's a lot more good in the world than there is bad and I continue to believe that," says the talk show host.
In a monologue for Tuesday's show, which was taped yesterday, the host reflected on the tragedy that claimed the lives of 59 victims and injured over 500 and shared what she and her viewers can do going forward.
"I am very happy you are here today. I am hoping we can fill this room with love, and prayers, and hope. That's what I want right now," she said at the top of the show. "This show is airing on Tuesday, but we are taping on Monday and we all woke up this morning to the news of the horrific shooting in Las Vegas. My heart is broken for everyone affected by what happened there. I mean, we were just in Las Vegas a few weeks ago and when you think of Las Vegas, it's a place to escape and have fun and you never imagine anything like this could ever happen."
"There's so much going on in the world right now – people are recovering from hurricanes, the devastation in Puerto Rico and on top of all that, something like this happens," she continued. "I don't know about you, but I feel sad, I feel anxious, I feel helpless. And it's very easy to lose hope, but we cannot do that. We cannot do that. I always say that there's a lot more good in the world than there is bad and I continue to believe that. And that is what we have to focus on. I see it everywhere. You look in Las Vegas and people were helping each other. People lined up at 4:30 in the morning just to donate blood."
"It is hard to do a show on a day like this. When I woke up today, I think how am I going to do a show? But it's also days like this that I appreciate my job more than ever because I get to focus and shine a light on the people that do good in the world," she added. "If you need a reminder of all the people out there that we have shown you that do good, here are a few of the people who inspired me."
What followed was a montage of local heroes who have appeared on her show.
"The world is full of amazing people. Good will always win. Love will always win. We will continue to shine a light on those people on our show," she said. "I am going to try to give you a show, every single day, what we want to do is give you an escape from whatever is going on in your life, whatever is going on in the world and that is what we're going to do today. Today is going to be a fun day."
DeGeneres also encouraged viewers to visit EllenTube.com, where there are links to help raise funds for victims of the shooting and hurricane relief.