The rules of the "Truth or Dare"-themed game are simple: Each contestant gets to choose between answering an incredibly revealing question about themselves or their work, or eat some downright disgusting items like fish eyes, bird saliva, giant water scorpions, turkey testicles and dried squid ice cream.
The game began with the "Santa Clarita Diet" star squirming after she was asked to reveal which talk show appearance was her least favorite to do, the options being Stephen Colbert, Jimmy Fallon or Ellen DeGeneres. Barrymore simply couldn't choose though, saying he picked three of her "favorite people." For that, she had to throw back some bird saliva.
When put in a similar situation for Round 2, however, Barrymore was more inclined to answer. Why? She had zero desire to taste a turkey testicle.
"Rank your costars from most to least talented. Adam Sandler, Hugh Grant and Jake Gyllenhaal," Corden asked. Without hesitation, Barrymore put Jake at the bottom of the pack. "Jake Gyllenhaal, so I don't have to eat a turkey ball," she said. "When I run into him next time, it'll be like, 'Dude, it was like selling you down the river or eating turkey's balls.' I don't even care if he hates me. Oh god. I literally am doing this because I just, I won't make it. I'll say Adam, Hugh, Jake."
The turkey testicle reared its ugly head again for Corden, however, who ate it instead of revealing who was the most difficult guest he's ever had on his show.
Other questions in the game included asking Boyega how much money he made from his work in the "Star Wars" films and to spill the details on the last time he "got so drunk you threw up." One of those ended with him chewing on a crispy scorpion.
Watch the video above to see what Corden ended up stealing from Mariah Carey's home while waiting on her for a "Carpool Karaoke" taping. See more "Spill Your Guts" segments below: