Barr previously ran for president herself and voted for Trump, two decisions Kimmel was very curious about, but he also brought up a past tweet when Barr called 2016 Democratic presidential nominee Hillary Clinton a murderer, even though Barr was a good friend of Clinton's at one point.
"What happened? I think you accused her of being a murder on Twitter, didn't you?"
"I did not," Barr protested, to which Kimmel laughed out, "Well then, you know I'm going to find that tweet in the next 40 seconds."
Barr said she "had some disagreements with her foreign policy," prompting co-star John Goodman to joke, "She had one."
"Listen, never mind her foreign policy. How about Captain Whacko we have running the country?" Kimmel asked his guest. "I'm shocked because I know you were a very socially liberal person."
"I'm still the same," Barr argued. "You all moved. You all went so f-cking far out, you lost everybody." I mean seriously, a lot of your audience -- including me -- no matter who we voted for, we don't want to see our president to fail."
"And yet we've seen it over and over again," Kimmel retorted.
"Roseanne" returns to TV with brand new episodes this coming Tuesday, and will play into the state of the nation's political discourse, with some members of the sitcom family being Trump supporters and others being critics.
Barr did not particularly defend Trump's behavior or actions since he's taken oath, but she did share this patriotic wisdom: "It's up to us to make this government work, no matter who's president. It's up to us to do our jobs as citizens, and if we don't like something, let 'em know you don't like it. And then you got another election in two years, get out there and vote."