While Jolie mentioned Maddox will be attending a university this fall, she didn't specify where he will be enrolling -- which could very well be out of concern for the famous child's safety.
Jolie also talked to People about a current global affairs program for children she's creating with BBC.
"We enjoy reading the kids pullout of the New York Times and look at National Geographic," Jolie said. "But as a parent, I felt there wasn't that one vetted and reliable internationally-minded news program tailored for children that we could sit down and watch together each week. That is what I hope this will be for our family and other families."
Earlier this week, Jolie, who shares eldest Maddox, Pax, 15, Zahara, 14, Shiloh, 12, and 10-year-old twins Knox and Vivienne with ex Brad Pitt, told the publication she hasn't ruled out running for office someday.
"Never say never, [but] right now, I am looking to others for leadership."
Jolie has gained international recognition for her work in helping refugees flee war-torn countries with the UNHCR. She also uses her celebrity platform to advocate for women's empowerment and safety all over the world, including working with the Preventing Sexual Violence Initiative (PSVI), which seeks to end the use of rape as a weapon in war.
"I try to speak for what I believe in," Jolie said of the causes she backs, which includes not only changing international laws that treat women like "second-class citizens," but enforcing those laws once changed.
"If you look across the world, there are far too many women and girls who are not only not seeing progress, their rights are slipping away from them," she said. "We also have to enforce [the laws after we change them]. So one of the things we are putting forward now is a proposal for a permanent international body to investigate war crimes, including mass rape and other sexual and gender-based violence."
In 2012, Jolie and former British foreign secretary William Hague founded the PSVI, and they've seen significant progress in terms of "awareness and discussion."
"Many more countries have made commitments," she said. "For example, 156 countries have pledged not to include amnesties for rape when they are negotiating peace agreements. It is hard to believe, but peace treaties routinely grant immunity to people who've carried out the most disgusting, violent crimes against civilians. So we have to make sure all those countries live up to that commitment."