"The Conners" star is stepping away from the show she created after nine years to be replaced by Marie Osmond in the fall.
UPDATE at 12:00pm PT on 8/2/2019: In another moving moment from Gilbert's final episode, she was surprised by wife Linda Perry and Sara's daughter, Sawyer, who performed a special song for the exiting host.
"I want everybody to know that this is a true, very inspiring human being here that is always trying to advance herself and everybody around her," said Perry, before bringing out Sawyer, one of Gilbert's daughters with ex Allison Adler.
Watch the performance of her original song, "Mama," below.
There wasn't a dry eye on the panel as "The Talk" creator and co-executive producer Sara Gilbert taped her farewell episode for air Friday, and no exchange was more heartfelt than between Gilbert and fellow original co-host Sharon Osbourne.
Gilbert recalled fighting for Osbourne to be on the show because she was so unabashedly fearless and herself.
"I know this is like completely unprofessional, but right after she got the job, I called her and I was like, 'I don't know what I'm doing. How do I do this?'" Gilbert confessed. "And she said, 'Just be yourself' and you gave me permission to do that over these years."
"The Talk" launched in 2010 with Gilbert and Osbourne sitting alongside Julie Chen, Marissa Jaret Winokur, Holly Robinson Peete and Leah Remini. Only Chen would continue beyond that first season, sticking with the show until sexual abuse allegations levied against her husband and former CBS head honcho Les Moonves precipitated her stepping away from the daytime talker.
"We've been there with each other and for each other through so many moments," Gilbert tearfully told her friend. "I have to figure out how to not see you every day. I'm going to be sitting in your yard."
Osbourne echoed Gilbert's sentiments, and her tears, with heartfelt words of her own. "Coming every day, seeing Sara -- she can read me, I can read her. If there's anything on my mind, I tell Sara," she said, breaking down. "Now, it's like, I won't have Sara here."
She even praised Gilbert for her support during her husband Ozzy Osbourne's health scare. "While my husband's been sick, Sara's just gone out of her way to find little things that she knows he'll like and buy for him and he considers her a friend too."
She's like a sister that I never had. I can tell her things and she gives me good advice. I know if I tell her things it won't go anywhere else. It's like a sacred thing," Osbourne continued. "It is like not having your sister with you anymore and it's going to be hard."
There were more goodbyes as well from Gilbert's other co-hosts, including Sheryl Underwood who admitted to being amazed that "the girl from 'Roseanne'" was part of the show. Hers was an emotional and beautiful tribute to Gilbert as a co-worker, a woman and a friend and how happy she was to be the "wacky black cousin" at her wedding.
Eve had nothing but praise for Gilbert as well, even going so far as to say, "I feel smarter sitting next to you," While Inaba thanked Gilbert for creating this space for women to grow and be their authentic selves, always pushing to be more genuine and more true. And that's something she does through example.
You can check out their full tributes below:
Sara Gilbert's last episode of "The Talk" airs Friday August 1 on CBS. Marie Osmond has been tapped to replace Gilbert on the panel for the show's tenth season, kicking off September 9, while Gilbert will remain involved as a producer.