"I'm not going to stand by this, it's ridiculous!" said 'The View' cohost during the tense conversation.
The sitdown got off to an awkward start as, right off the bat, Abby Hunstman began asking her about her split from soccer star Adil Rami, who she accused of cheating on her and causing her "physical and emotional torture." He denied the allegations.
"Oh what else is new, not like it's my first mistake," said Anderson, adding that she didn't "want to give him any attention, that's what he wanted."
"Just to trust your instincts, that's what I learned in the whole thing," she continued. "I knew all along ... but the issue is very important because many women go through this and it's just horrible. I loved being in France, that was the good part, I learned a little French and now I'm home, I'm back in Vancouver Island, which is my home."
When Huntsman brought up "what she went through" yet again, Anderson steered the conversation in another direction. "I'm a woman, we all go through such wild things. That's why I love this show too, our women have to get together and fix some of these problems.," she replied. "There's so many issues that need to be discussed, the human condition, our natural way of living. I really blame the Republican party for most of the issues that we're facing when we're facing climate change, climate deniers and the threat of nuclear war."
The subject then shifted to Assange, who is awaiting an extradition hearing in a London prison following his role in the leak of several confidential documents via former soldier Chelsea Manning, which were damning to the US military. Anderson has been a fierce advocate for Assange, who she has visited behind bars.
"His health is really deteriorating," she said of her friend. "He's lost about 30 pounds since I saw him and he was very thin at that point. He was wearing two pairs of sweatpants trying to be strong and look good for me because he always feels like people wont fight for people if they're not resilient and he is the most resilient person I've ever met."
She went on to call it "devastating" to see how "people have fallen for this smear campaign, especially in America" against Assange, who she supports. "It's really frustrating, I hope he doesn't get extradited, I don't think he'll make it. I don't think you're protected in prison, look at Epstein. There's a lot of danger surrounding his life."
When McCain asked about reports Assange had defecated all over the place while being held in Ecuador's Embassy in London, Anderson said that allegation was part of the "smear campaign" and wasn't true -- before then saying, "What would you do if you were locked in a room for 6 years?"
"I wouldn't be a cyber terrorist which he is, he hacked information" McCain shot back. "He's not a cyber terrorist, he didn't hack," replied Pam. Anderson then asked, "How many people has the American government killed innocently and how many has WikiLeaks?" which got applause from the audience. "Oh calm down, sir," McCain said to one especially energetic supporter.
Joy Behar then asked if she felt Assange was "responsible for giving us Trump," as he exposed emails sent from Hillary Clinton's private server and leaked others from her campaign chairman during the election. "Hillary Clinton is responsible for Trump," she replied. "He wasn't helping Trump, he was trying to tell the American people true information that Hillary was doing to make an educated choice and I think FBI put the nail on that coffin."
McCain took over again, asking if Anderson believes Assange has put spies at risk by releasing classified information -- she didn't -- before Whoopi Goldberg asked what his main goal was for all of this.
"Obviously, there's other people who can speak better for him than me, but he believes in justice, he believes in honesty, believes in exposing governments for what they're really doing and people have the right to know what's happening," she responded. "His whole intention is to stop these senseless wars. War is a business, it doesn't help anybody. He's not saying his opinion, he's giving information. He's a publisher and he supports whistleblowers."
"He certainly stirred up a lot in this country," Abby interjected, before McCain took issue with that characterization of the situation. "He's a cyber terrorist!" she exclaimed. "I'll say it. I'm not going to stand by this, it's ridiculous ... 'stirred a lot of trouble.'"
The show then went to break, as McCain was seen saying something to Huntsman before they went to commercial. When the show returned, Anderson was still there, though they shifted gears to talk about Playboy, the #MeToo movement and her infamous "Baywatch" swimsuit.
"The View" airs daily on ABC.