Stars Who Have Spoken Out On Weight Loss Drug Trend In Hollywood

Celebrity By TooFab Staff | 3/27/2023 11:19 AM PT

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The use of Ozempic -- a popular diabetes medicine -- and other prescription medications which have been adopted by many for their weight-loss side effects have become a hot topic in Hollywood. So far, many stars have criticized the drugs, fought back against accusations that they're using it or have openly admitted they have no issue with the trend and have even tried it themselves. See who stands where below!

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Amanda Bynes shared via her Instagram story that she is starting Ozempic with the goal to lose 40 pounds. She wants to " look better in paparazzi pictures" and to stop photos of her "double chin from strange angles." The former actress told fans, "I’m going on Ozempic. So excited. I’m 173 now and I hope to get down to like 130, which would be awesome."

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Lizzo revealed on the Just Trish podcast that she has tried Ozempic and other weight loss drugs, but stopped them to do the "mind over matter" method. "It’s just the science, for me, calories in vs. calories out. [...] It [Ozempic] makes you feel full. So, if you can just do that on your own," the singer explained. She also ditched her vegan diet for whole foods/proteins, saying, "I was consuming a lot of fake meats. I was eating a lot of bread. I was eating a lot of rice, and I had to eat a lot of it to stay full. But really I was consuming like 3,000 to 5,000 calories a day."

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Dolores Catania shared that her Mounjaro "stopped working" and she's gained 20lbs. "I'm having a really hard time right now," she admitted on Jeff Lewis Live. "I’ve been looking for therapy for all my friends. I’m really having a bad time with this," she continued on. The Real Housewife believes that the weight gain could be related to her cardiac condition that caused her to have a heart procedure. As a result, she is taking a break from her medication as she takes "10 pills a day" as a part of her post-op care.

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Real Housewife of London Amanda Caroline Cronin revealed she micro doses on Ozempic to remain a size 0. She went on the diabetic drug after gaining 20lbs during menopause. She told the Daily Mail, "‘I decided to lose weight as my dress size crept up from six to eight to ten in two years. I was a double zero all my life – now I'm a size zero in couture." She also raved how the drug helped her give up alcohol and improve her overall blood work. She continues to micro dose a few times a year while also sticking to a Mediterranean diet, and doing pilates, swimming and walking for exercise.

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"I can't believe this is me now #mounjaro #weightloss #bodydismorphia" Rosie O'Donnell captions an image of her slimmer self on stage on Friday, May 23 -- two months after talking about her ongoing weight loss on the drug, which she said she's on for her diabetes, while also crediting home cooking, and more than two years since she first revealed her doctor had put her on both Mounjaro and Repatha in November 2022.

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Renee Graziano posted transformation pics on Instagram and wrote about her health journey, including the role of Mounjaro: "OH BABY 😍 IM DOWN 52lbs … I love sharing my weight-loss journey with y’all because truthfully, I’ve been so hard on myself behind the scenes [...] Between taking my weekly MOUNJARO shot for the 1st 5 months, the. making sure I took the right supplements (dm me I will share what take) weekly chats with my therapist and doing all the work behind my insecurity, I haven’t felt the need for a plastic surgery short cut. [...] My mind is clear and My body has transformed..."

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Eric Stonestreet has become a spokesperson for Mounjaro after using it to treat his Type 2 Diabetes along with lifestyle changes in diet and exercise. The actor initially kept his condition a secret, but decided to get more serious after watching his father battle diabetic neuropathy. He claimed the drug changed his mindset: "If I don't do something along with it, I'm disappointing it. [...] Now I need to contribute my part. And it turns out that when you do that and make some really great choices, weight loss is also a byproduct of that.”

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Kyle Richards and Mauricio Umansky's daughter, Sophia, shared an unexpected side effect of taking the drug Mounjaro. After three months, she has developed severe hair loss from rapid weight loss and posted a video of her shower wall and drain surrounded by hair. "At the rate that I've been losing hair, I'm gonna be bald in about a week," she told fans, "all throughout the day if I just [run my hands through my hair] I'm pulling out, like, piles of hair." She believes the hair loss comes from not having enough protein/vitamins and has since adjusted while looking for other remedies.

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Macy Gray revealed she was "p----d off" with Ozempic after having a negative reaction. In an interview, she exclaimed, "I'm the only person in the world who had a bad reaction to Ozempic. I'm so p----d off. All my friends are 30 pounds smaller, and I just got sick." She continued on about her body, saying "But I'm doing well health-wise. I'm 57 and I haven't really started to feel anything going bad."

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Kendra Wilkinson shared on Instagram that she started weight loss shots, but threw them away after only taking one. She then joked that she would do "mental Ozempic." The former Playboy Bunny followed up with another Instagram story to answer why she stopped the shots so suddenly, explaining that she's happy with "a little weight gain" and that she's "heard too many horror stories."

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Meghan Trainor and her husband, Daryl Sabara, have revealed they are taking the weight loss drug, Mounjaro, together. Trainor confessed on the Workin On It podcast that they chose the prescription after extensive research and deciding to go on the lowest dose. They also exercise and eat balanced meals to work with the medication: "We were like, ‘We have to make sure we don't lose muscle, that we worked so hard gaining all those years.' And we stay in the gym, we work out, we eat right. And we just noticed that we were less hungry [...] I have no shame being on it and talking about it.”

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Robbie Williams turned to an appetite-suppressant drug to lose weight, saying, "I'd stopped eating and I wasn't getting nutrients" -- including Vitamin C, leading to a scurvy diagnosis. "A 17th century pirate disease," he told Daily Mirror, adding that his weight loss decision came after his first depressive episode in a decade, something he suspected was died to his diet. "When people say: 'We're worried you're too thin' that goes into my head as 'jackpot. I've reached the promised land,'" he said of his mindset at the time.

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Meghan Trainor revealed she's used the weight loss drug Mounjaro after people commented on her body following Billboard's Women in Music. On Instagram, she wrote, "No, I don’t look like I did 10 years ago. I’ve been on a journey to be the healthiest, strongest version of myself for my kids and for me. I’ve worked with a dietician, made huge lifestyle changes, started exercising with a trainer, and yes, I used science and support (shoutout to Mounjaro!) to help me after my 2nd pregnancy. And I’m so glad I did because I feel great."

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Nikki Glaser got candid on The Tonight Show about Ozempic. As a user of the diabetes drug herself, she posted her transformation on Instagram and explained, "Oh, I love it, I love. I’m like, do it, do it." In response to Ozempic critics, Glaser exclaimed, "I feel like there’s this shame. And the shame is only from thin people who want you to stay fat. [...] It’s suddenly all these thin white women who are like, ‘Diabetics need their meds.’ No, I think you’re upset that Kathy Bates has a thigh gap. She’s coming for you."

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Amy Schumer says that 3 years after "puking" from trying Wegovy, she's now trying Mounjaro, as well as estrogen and progesterone for her perimenopause symptoms, and she says her experience has been "great." Schumer added, "It’s not covered by insurance unless you have diabetes or like severe obesity, which most of the internet thinks I have. But I’m having a really good experience with it and I wanted to keep it real with you about that."

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Hacks' Meg Stalter called out those who "lie" about using Ozempic, saying, "We know if you’re on it because you’re s—ing your pants." She added, "How is that hotter than being fat? That is insane to me. I would rather be 500 lbs. than s—ing all day. That’s so gross ... if you’re taking a drug on purpose just so you lose 10 pounds then, honey, we liked you a little chubbier."

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RuPaul's Drag Race Season 9 runner-up Peppermint told Page Six she has lost 100 pounds, after years of struggling to manage her weight, admitting she first got on Ozempic after she was "diagnosed as pre-diabetic a couple of years ago." She added, "I’m very grateful that I’m at a point now where I have access to levels of healthcare that I didn’t have before ... I was really worried that my life was going to change irreversibly once I crossed that threshold [into diabetes]."

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Amy Schumer shared on The Howard Stern show that when she tried Ozempic almost three years ago, it caused her to be "bedridden" with nausea. She explained her bad reaction was due to the GDF15 gene, that causes her to be more prone to vomiting. "I lost 30 pounds so quick. I looked great and I couldn't lift my head off the pillow, so what's the point?" she shared, adding, "I tried it and I was vomiting and I'm in bed and my son's like, 'Can you play tag?' I'm like, 'I can't.' I was shriveling."

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Josh Gad is using GLP-1 medication for weight loss, calling it a "miracle drug" after losing 40-lbs on a different drug that caused intestinal issues. "I'm figuring out this new one, and it is life-changing," he said on Armchair Expert, adding that he knows he still needs a "healthy relationship" with both food and exercise. "Sometimes I feel like I'm cheating myself by doing this," he added, saying the weight loss made him wonder, "I've always been the funny fat guy. Can I be the funny skinny guy?"

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Real Housewives star Cynthia Bailley shared about her negative experience with Ozempic. In an interview, she explained she tried Ozempic because her peers were using it but ended up stopping, explaining it took the fun out of eating: "I didn't enjoy it because when I get my crab cake and my salad and my oysters and my BBQ ribs, I want to enjoy it. I was just literally looking at the food like, 'What is this? What am I supposed to do with this?'" She doesn't extend any hate to people who use Ozempic, but she prefers the support system and more traditional methods of Weight Watchers.

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Model Brooks Nader shared that she briefly tried Ozempic during its early popularity, but ended up giving up the weight-loss drug for Dancing With the Stars. In a recent interview with Us Magazine, she said, "It made me really nauseous. I liked it — I am not going to lie — and when I went on Dancing with the Stars, I could not do both." Nader added the drug made her lose "a little bit of the motivation and the strength to work out" and "It was one or the other, and I picked [DWTS]. I put the shot away."

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Bonnie Chapman, daughter of the late Beth Chapman and Dog the Bounty Hunter, went from 196 pounds to 126 pounds. However, she used the weight loss drug Tirezepatide after having a negative experience with Ozempic. Of the latter, she said, "I could not eat without feeling nauseous. I could not eat at all, sometimes. My body did not like it." However, with Tirezepatide, she said she was able to overcome nausea within a week, eat smaller portions and feel full, while not actively craving foods that could contribute to weight gain.

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Comedian Jim Gaffigan confirmed to PEOPLE he's lost 50 pounds thanks to Mounjaro. This after telling Us Magazine he realized he needed to make a change when he was around "probably 270" pounds. "I was so paranoid that I was going to be nauseous that I kind of put it off, but then it kind of worked," he told the outlet, adding it's "odd" there's a "stigma" around using the drugs. "I'm kind of like a square Midwesterner. I will never look super thin," he added.

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Dog the Bounty Hunter's daughter Bonnie Chapman shared an Instagram video, in which she revealed she's "lost 58 pounds in the last 10 months" by using tirzepatide, and praised the weight loss drug. The 25-year-old said it was "impossible" for her to lose weight in the past due to having PCOS. Chapman said tirzepatide made it so she processes food "a little bit slower" so she "stay[s] full longer." She added, "Here I am, 10 months later, I am so in love with the results. I am able to look at myself in the mirror and feel so proud of where I've gotten. I am at my goal weight."

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Bunnie XO

Bunnie XO shared her recent experiences with tirzepatide on her Dumb Blonde podcast, saying that after five days she almost went to the hospital she was so dehydrated from diarrhea. She praised husband Jelly Roll's tour nurse: "She gave me two IV bags and some magnesium, and I felt like a new woman." She says she's lost 4 pounds in 2 weeks, but is taking the meds "to regulate my hormones because I believe I have PCOS." It's been an up-and-down experience, but she told her followers she's "back to pooping normally in case everybody wants to know."

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Fat Joe is no longer living up to his stage name, as the rapper told 'US Weekly' all about his journey with Ozempic and losing over 200 pounds. He explained, "Ozempic says you may only have two pieces of your favorite stuff," and while taking the Type 2 diabetes drug, he cut out most carbohydrates and sugars. For example, in the morning, he might only eat the corner of a piece of toast to supplement the rest of his meal. As he went on his journey, he explained a body is like a computer and responds to what one programs/eats, and that as he has gotten older, his physical health has been tied to mental health. Now 200 pounds down, Fat Joe, isn't really "fat," but he assured his fans that the stage name is not going anywhere.

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James Corden revealed he tried Ozempic, adding, "and it won’t be surprising to you when you look at me now, that it didn’t really work." He explained trying it "for a bit" made him realize his eating habits had nothing "to do with being hungry," so suppressing his appetite didn't help. "It is not that," he said, "it's something else."

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After showing off her recent weight loss -- writing, "FINE BOTH WAYS 😮‍💨😮‍💨😮‍💨" -- Lizzo was met with Ozempic speculation by fans in the comments. In a followup video, she wrote, "When you finally get ozempic allegations after 5 months of weight training and calorie deficit" -- before hitting back at one follower asking if she used weight loss drugs or cocaine by saying, "Whyyy do you follow me?"

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After admitting to using Ozempic in early 2024, RHOSLC's Heather Gay later said she "can't win" when it comes to her weight. "I got shamed for being overweight and I got shamed for being on medication," she told E!, adding, ""I'm feel the same. I feel like I liked myself then, I like myself now. It's just Ozempic became available and it worked for me."

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Lottie Moss, model and half-sister of Kate Moss, says she started noticing extreme side effects -- like losing color in her face -- after losing 15 pounds in a matter of weeks on Ozempic. At one point, she couldn't keep food or water down and was taken to the hospital, where she suffered a seizure and learned she was taking double the dose for someone her size. "This is a warning to everyone. Please, if you're thinking of taking it, do not take it, it's so not worth it," she said.

Read More About Terrifying Ordeal

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After receiving compliments on how "tea" her body looks in a new selfie, Ice Spice said to her followers: "I actually came on here to talk about that real quick. Cuz I was like, bitch, I wish y'all never learned the word Ozempic. That’s one thing I wish. Oh my God! Like what even is Ozempic? What the f–k is that? Genuinely, what is that? Like, you lazy bitches never heard of the gym? It’s called the gym, it’s called eating healthy, it’s called being on tour."

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After previously opening up about using Ozempic as a tool to use weight after gaining 18lbs. during her IVF journey, Real Housewives of Dubai star Caroline Stanbury told Page Six she vomited after drinking while on the drug. "If you haven't projectile vomited on Ozempic, you haven’t lived yet," she shared, saying it happened to her at The Abbey bar in West Hollywood. While she has cut back on drinking, it's mainly due to "horrible hangovers" and not because of her experience at The Abbey.

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After telling TooFab her "body didn't take it well," Macy Gray speaks more about her Ozempic experience on The Surreal Life -- admitting she's "kind of a vain person" and started taking it before the show because she "didn't want to be super fat on TV." Describing her side effects, she said, "My stomach hurts. I've just been really constipated. I was up all night."

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Bella Thorne shared she hasn't "been feeling good about my body for a while," saying weight loss drugs are "setting all these crazy beauty standards that nobody can keep up with unless you're on Ozempic." In a bikini video she added, "I'm finally feeling good about myself ... so Ozempic, you can," she continued, before flipping off the camera.

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After Alabama Barker turned to weight loss drugs "because I'm tired of being fat and photographing like a damn ogre," Abigail Breslin shared on Instagram, "This makes me super sad." Breslin, who is "several years free of my own ED," added, "I have zero judgement towards people who take medications like this but the fact that she started taking weight loss meds because of online comments is absolutely devastating. Please everyone, let's just be kinder. You have no idea how traumatizing these kind of comments can be. She’s a beautiful girl ... this is awful. And it makes me really sad. Sending love her way."

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In a makeup tutorial, Alabama Barker revealed she is using weight loss medication, without specifying which one. "I have this thing where I photograph so ugly and people are like, 'You're so fat and you're so ugly,'" she shared, adding that she doesn't believe she looks that way in person. "But I'm on weight loss medication because I'm tired of being fat and photographing like a damn ogre,'" she added.

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Shanna Moakler revealed she started using Mounjaro to lose weight after the deaths of both her parents in 2023. "I was in a very, very dark place. I stopped dieting. I stopped exercising. I just ate like s--t," she said of her weight gain. "I was so devastated, and I missed my f---ing mom and dad. I was like, 'I'm going to f---ing eat the pain away."

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Kandi Burruss reveals she tried Ozempic but didn't see any results. During an episode of Page Six's Virtual Reali-Tea podcast, she shared: "I didn't lose any weight! When you see it worked for other people and it doesn't work for you, it makes you depressed. Realistically, it makes you feel like, 'What is wrong? Why is it not working for me?' My doctor was like, 'I don't know what the problem is, I'm not seeing this in other people.' It didn't curb my appetite."

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Adam Lambert admits to using controversial weight loss medicine Mounjaro, revealing on an Instagram live that he lost nearly 60 pounds.

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Ashley Benson hits back at claims she's using Ozempic after a recent selfie she posted, one user wrote: "how was she JUST pregnant?!?" Benson replied on her story, "Comments like this are so funny to me. I know a lot of people take ozempic and that’s totally fine. To each their own. But don’t discredit people who also work very hard to get their body back like I’ve done with mine. Getting back to work forced me to focus on my health and working out and I wanted to feel confident and good about myself. And again couldn’t do this without my @melissawoodtepperberg app"

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Jesse Plemons denies using Ozempic after his recent dramatic weight loss. Speaking with the LA Times he reveals: "It’s really unfortunate that I decided to get healthy when everyone decided to take Ozempic. It doesn’t matter. Everyone’s going to think I took Ozempic anyways." He continued, "Several people talked to me about intermittent fasting and I just gave it a shot and was surprised at how quickly it was effective."

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Mama June Shannon reveals she lost 30lbs with the help of a weight loss medicine, telling ET: "Even though I'm losing weight, I'm only about three to four pounds a week. It isn't as fast as a gastric sleeve or a gastric bypass, but it is doing it, like, more safer." She added, "I still have about 74.2 pounds to go." The TLC star told In Touch Weekly that she's on "triglycerides" after previously trying semaglutide. (However, she shared with other outlets, including Page Six and Us Weekly, that she's on tirzepatide, which is sold under the brand names Mounjaro and Zepbound.)

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RHOC star Braunwyn Windham-Burke jokes fiancée Jen Spinner is "starving" now that she's started taking Ozempic. "I don't want to cook because I can't eat! Feed yourself!" she quipped to Us Weekly, adding that she feels "amazing" and loves that "I can fit in my old clothes." Bottom line: "I needed help. I got help. My wife is hungry."

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Kelly Clarkson revealed she used a drug to aid her weight loss journey on her talk show. "Mine is a different one than people assume, but I ended up having to do that too because my blood work got so bad," she said. "You know what’s funny? Is I didn’t see it. My doctor chased me for like two years and I was like no, I’m afraid of it, I already have thyroid problems. I was afraid. It’s something that aids in helping break down the sugar. Obviously my body doesn’t do it right. But seeing yourself… I didn’t see it."

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Whoopi Goldberg revealed she "weighed almost 300 pounds" in 2021 when she filmed Till, before adding that, "one of the things that's helped me drop the weight is Mounjaro. That's what I use." During an episode of The Kelly Clarkson Show, she added she lost the weight of "almost two people." Goldberg explained, "I'm doing that wonderful shot that works for folks who need some help and it's been really good for me, it's great for people like us who have, you know, issues."

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Food Network's Sandra Lee said she recently lost 10 pounds using an unnamed weight loss drug -- but it didn't go well. "One of them put me in bed for an entire week," she told Fox News Digital. "I lost ten pounds, but I was sick as sick could be. And so, I don’t know, for every person, it's what their body can handle and tolerate. It wasn’t for me."

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Jon Gosselin opened up about his journey with Ozempic, sharing that he wishes he started using it many years ago. "You know what's annoying? The regret of not starting it 10 years ago," he told Page Six. The reality star also revealed that he's lost 32 pounds since he started taking Ozempic in February. "I feel amazing! Like, why didn't I do this sooner? Maybe it wasn’t the right time," he said, also adding that the medication has helped him "stop drinking" and get his appetite "under control."

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Sunny Hostin also revealed she started using Mounjaro after gaining 40 pounds during the pandemic. Though she says she got "nasty" messages about how "skinny" she looked, she said her cholesterol dropped and she now fees better and thinks she looks better than ever, "and that's what this is about for people."

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Ree Drummond denies the use of Ozempic after recent weight loss, opening up in her blog post, she reveals: "I did not take Ozempic, Wegovy, or similar medications, I know this has been a big topic in recent years, so I thought I'd add this paragraph. For me, the simple, boring truth is that when I set out to lose weight in January of 2021, I had never heard of that class of drugs. And to be honest, if I had heard of them and had seen all the results that are out there, I might have been tempted to try them," adding: "You'll never hear a second of judgment from me about people who choose that direction!"

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Claudia Oshry, also known as Girl with No Job on TikTok, says she's " so hungry all the mother-f---ing time" months after she stopped taking Ozempic. Oshry lost 70 pounds from October 2022-November 2023 -- and now says, "I cannot stay full, it's impossible. I just had a 12 oz. steak and I'm starving so I'm eating popcorn. How are we staying full?"

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Rob Lowe shares his thoughts on the weight loss drug trend in Hollywood, when interviewing with People, he reveals: "I see people who are taking all the new weight loss drugs and that's great, and it's really changed their lives. But my concern always is, okay, now what?" He continues, "What’s the plan for the longevity of everything? I never ever talk about diets, I talk about lifestyle."

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Kelly Osbourne reveals why she supports the use of Ozempic in Hollywood. When asked how she felt about the trend, the former reality star didn't hold back her support, "I think it's amazing and I think it's great for them," she continued, "There are a million ways to lose weight why not do it through something that isn't as boring as working out? People hate on it because they want to do it, and the people who hate on it the most, the people who are secretly doing it are pissed off they can't afford it."

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Scheana Shay denied using Ozempic after recent weight loss -- and instead blamed it on the fallout from Tom Sandoval's affair with Rachel Leviss. During the season 11 premiere of Vanderpump Rules, the reality star shared how the affair affected her body, saying: "You know how many people have asked me if I’m on Ozempic lately? No, it’s called Scandoval." She also said she cut alcohol and marijuana out of her life while on Zoloft -- which she started taking when the Scandoval affected her OCD and anxiety.

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50 Cent insists he hasn't used any sort of weight loss medicine to lose his weight, the rapper took to Instagram saying: "Everybody talking about weight loss. I was in the gym. I was working the f--k out, man. Who says Ozempic? I was running,” he continued, “I was running, I was doing what I had to do."

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Dr. Terry Dubrow said he tried Ozempic because many of his patients were on it and he "wanted to see what it was like when you're not diabetic." While he said he was a "huge fan" of the "miracle" drug, he didn't like the "low-grade nausea" that came with it for him and felt it "really took … all the joy of eating away."

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In his 2024 memoir, Boy George reveals he had a tummy tuck, tried Ozempic and is currently using Mounjaro. "I have struggled with my weight most of my life and being under public and media scrutiny doesn't help," he wrote. "I love food and I can't control my appetite, but I think I have finally got it under control. Well, I'm on Mounjaro. Isn't everyone? Trust me anyone who was fat last year and is now skinny is on the wonder drug."

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Oprah Winfrey confirmed that in addition to regular exercise and lifestyle changes, she also added weight-loss medication into her routine after she "released my own shame about it." Though she wouldn't name which product she uses, she said she uses it "as I feel I need it, as a tool to manage not yo-yoing." She added, "The fact that there's a medically approved prescription for managing weight and staying healthier, in my lifetime, feels like relief, like redemption, like a gift, and not something to hide behind and once again be ridiculed for. I'm absolutely done with the shaming from other people and particularly myself."

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Jennifer Fessler claims her weight loss drug use landed her in the hospital. On an episode of Two Jersey Js, the RHONJ star said, "I have been on, and I'm not going to call it Ozempic — that's been the umbrella name. But I've been on semaglutide for over a year now, and I've lost maybe 22 pounds." She continued, "I'm not afraid of Ozempic and I will tell you I have had an experience that was not good — and I'm pretty positive it was about the semaglutide — where I had to go to the hospital for an impacted bowel … and I'm still not nervous about it." She said she wasn't eating healthy and became constipated, adding she was "to blame" for her medical issue.

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Maria Bello reveals she tried Ozempic, taking to Instagram to write: "I went through the first half of menopause during Covid and tried everything to keep it at bay. I took bio-identical hormones (and still do), dieted harder and faster but still managed to gain 15 pounds, tried Ozempic for a week but gave up after the constant nausea and vomiting, got rid of the waddle on my neck, tried Botox, fillers and lasers, face creams, cellulite machines, face threads, teeth straightening and more. I did copious amounts of therapy, including micro-dosing psilocybin, left Hollywood and all social media and at the end of it all finally moved to Paris." She said she hoped to share her journey to inspire other women to "embrace" menopause, instead of trying to "avoid" it."

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Rep. George Santos confirmed he uses Ozempic for weight loss in an appearance on Meghan McCain's podcast Megan McCain Has Entered the Chat. "In January 2022, I weighed myself in at 350 pounds and I said, 'No. This has to change,'" he explained. "In December 2022, I weighed myself in before the New Year rang in and I was 251 pounds, so that's 99 pounds in a year." Santos also revealed he was pre-diabetic, explaining: "It totally helped. I think the FDA should really consider looking into it and seeing it as an option for weight loss. Obesity is the number one cause of death in this country." Saying he'll likely be on it forever, he added, "It's fantastic ... I love it."

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Sharon Osbourne opened up about her 30-pound weight loss due to Ozempic during an appearance on Talk TV's Piers Morgan Uncensored, admitting she's now "too skinny." "It's just time to stop, I didn't actually want to go this thin, but it just happened," she said, adding that she's "probably put it all on again soon." The former Talk cohost -- who lost the significant amount of weight over a span of four months -- previously got candid about the unpleasant side effects, telling Bill Maher, "The first few weeks was f--king s--t because you just throw up all the time. You feel so nauseous. After a couple of weeks, it goes, and then you’re just fine, you feel nothing. Just not hungry."

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Tracy Morgan says he's on Ozempic and he "ain't letting it go." The actor appeared on the TODAY show on Monday and said the prescription was responsible for his transformation. "It cuts my appetite in half," he explained. "Now I only eat half a bag of Doritos." Then miming plunging a syringe into his stomach he said, "I take Ozempic every Thursday." Although the prescription drug was not entirely responsible for his current physique, as he noted, "I get up at 7 every morning, and I'm in the gym at 10. Then I go back to sleep. And that's my life."

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RHONJ star Dolores Catania -- who says she's "insulin resistance/pre-diabetic" -- confirmed she took Ozempic for two years, before her doctor switched her to Mounjaro, another anti-diabetic medication, earlier this year. "I'm down 20 pounds," she told The Sun, "Right now, I'm 137. I was 157 when I started." She told the outlet that the weight loss "doesn't happen overnight" and "it doesn't come off easy," also crediting workouts with her transformation.

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Raven-Symone issued a warning to those who used the diabetes medications solely for weight loss, while saying she has pre-diabetes in her family and is "more susceptible to getting diabetes" herself. Speaking with E!, she said, "I think it's very important we understand certain medications are made for certain people -- and to not take that away just for glamazon purposes. Do what you gotta do, just make sure you save the medication for the people who actually need it."

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RHOC star Emily Simpson revealed in an interview with Jeff Lewis that her doctor recommended Ozempic to her back in December 2022, after a blood panel showed she was pre-diabetic and had high cholesterol. She said it was "a great kickstart" for her because it helped curb her of her "bad" snacking habits -- but added she only lost 5-7 pounds while on it for just a month and stopped taking it because it made her feel "lethargic." She followed that up with lipo on her arms and a breast reduction in January 2023, has since "changed my diet completely" and now feels "the healthiest I've ever been."

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Pregnant Vanderpump Rules alum Stassi Schroeder appeared on Call Her Daddy with Alex Cooper and said of Ozempic, "Oh my god, I really want to try it when I give birth, the amount of times I've researched this being like, 'I mean, I think it's safe and healthy. Like, I think it's good for you. It's like taking vitamins.'"

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Amy Schumer revealed on Watch What Happens Live with Andy Cohen that she tried Ozempic, before giving it up. "Like a year ago, I tried it. I was one of those people that felt so sick and couldn't play with my son. I was so skinny and he's throwing a ball at me and [I couldn't]," she said. "And you're like, 'OK, this isn't livable for me.' But I immediately invested because I knew everyone was going to try it." She also urged those who do use weight loss drugs or have work done to "Be real with the people."

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"Shahs of Sunset" star Golnesa "GG" Gharachedaghi revealed she began using Semaglutide injections to help her lose weight. In the first four weeks, she went from 137 pounds to 126 -- but, in a followup post (pictured), said she would be cutting back on the drug after dropping more weight than anticipated. "When I started Semaglutide shots, I was 138 pounds. Now, I'm about 110 pounds. As you can see, I've lost a little more weight than I was anticipating to lose." She explained, "I decided I'm only going to weigh myself on the days of my injections just to document it. And on April 30, I got on the scale, and I saw 111 pounds. That's when I knew, it's time to cut back. That's when I started cutting down on units and going backwards and backwards until finally now, I'm just on maintenance."

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Tracy Tutor used Mounjaro, a weight loss medication similar to Ozempic, for about 8 weeks while filming Million Dollar Listing: Los Angeles. On the Jeff Lewis Has Issues podcast, she claimed she was unable to drink alcohol on the medication without "projectile" vomiting. "I had taken the [Mounjaro] shot, like, maybe a week before. One night we stayed in, and we had dinner, and I had probably three glasses of wine, maybe smoked a little hooch after, went to bed, woke up, was unwell — like, so unwell," she said, before detailing an incident during filming with a client. "I must've run like 200 feet, throwing up the entire way. The whole party, like, stops. Everybody’s looking like, ‘What’s wrong with her?’ It was a tragedy." She added it wasn't just a hangover, feeling "it was legitimately from the shot."

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Tim McGraw and Faith Hill's daughter Gracie opened up about her experience with Ozempic after a troll said her bikini body was due to the antidiabetic and weight loss medication. She responded, writing, "I did use ozempic last year, yes. I am now on a low dose of mounjaro for my PCOS as well as working out. No need to accuse when I have been open about it." The drugs are known to ease the symptoms of polycystic ovary syndrome.

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Charles Barkley confirmed he lost 62lbs in 6 months through working out and with the help of Mounjaro, a medicine similar to Ozempic. "I started at 352 and I'm down to 290," he said, adding that he takes the shot once a week and joking, "I have zero idea what it does, I'm not going to lie."

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Gina Kirschenheiter weighed herself in an attempt to "silence the noise" suggesting she uses Ozempic. The reality star posted a TikTok, captioning the video: "I'm a size 6. If I wasn't eating I would be a 2. Go kick rocks." She added: "I am very healthy, very average. Like all of us, I try to take my pictures at good angles [and] I stopped drinking a year and a half ago, I'm not on a weight loss drug and it's not my fault that you want to try and make something that's not there, my friend."

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Bethenny Frankel made it very clear she does not condone the use of Ozempic strictly for weight loss. The former "Real Housewives of New York" made an Instagram video referring to the drug as "NOzempic" and warning her audience by saying, "This is going to be scary because very thin people who have body dysmorphia and eating disorders are going to be taking this." She added, "Mark my words, we’re not going to hear about the s–t show of this for months and years to come… it's going to be a f–king s–t show."

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Jameela Jamil is one of the most recent celebrities to speak out about Ozempic after noticing fans discussing why everyone was so "skinny" at the Oscars this year. In a poignant statement on her Instagram, Jameela revealed that "A LOT of people this year took weight loss injections," which she noted "don't keep the weight off permanently." Jameela added that she wasn’t trying to be "judgemental," but rather wanted to keep her followers from being "triggered" or making “any sudden decisions, because of the images of impossible standards that come out today." "It's a temporary extreme," Jameela wrote. "None of this lasts. Very rarely is it unrestrictive and healthy. Don’t shame yourself because you don't look like these women tonight."

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Chelsea Handler admits that she was once on Ozempic but she didn’t even know it. She explained that her anti-aging doctor gave her the medication if she ever wanted "to drop five pounds" but didn’t explain what it was. She decided to try it out but only realized it was Ozempic when she began having symptoms. Chelsea says she’s no longer on the medication. "I'm not on it anymore. That's too irresponsible. I'm an irresponsible drug user, but I'm not gonna take a diabetic drug. I tried it, and I'm not gonna do that. That's not for me. That's not right for me," she said on the "Call Her Daddy" podcast. "I've injected about four or five of my friends with Ozempic because I realized I didn't wanna use it 'cause it's silly. It's for heavy people. Everyone is on Ozempic. It's gonna backfire, something bad is gonna happen."

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Over the course of the past year, fans have noticed that Julia Fox has lost a significant amount of weight. Due to her changing appearance, some accused her of using Ozempic -- but she says that's something she'd never do. "All these people are coming for me saying that I take the weight loss things...People are saying that I'm taking Ozempic or whatever it's called. I'm not and I've never have...I would never do that. There are diabetics that need it," she told Entertainment Tonight.

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"Real Housewife" Kyle Richards has also been called out for using Ozempic to lose weight but she's denied ever touching the medication. She explained that she'd never even heard of it until recently and is "offended" and "angry" that anyone believes she would use those methods to drop pounds. Instead, she says her weight loss is all natural and she puts in a lot of work in the gym. "I didn't even know about Ozempic until I'd already lost the weight I wanted to lose," Kyle told People. "I started losing weight eight months ago, actually, because I stopped drinking alcohol eight months ago. At first I was like, 'Why are they saying I'm taking this diet drug?' Then they thought, 'Well, maybe it's another kind,' because I was saying, 'It's not Ozempic.' It wasn't any diet drug ever, never touched it. So it really just frustrated me because I'm working out really hard."

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After Rosie O'Donnell recently dropped some weight, she explained that it did have to do with medication -- but she was taking it for her type 2 diabetes. In a TikTok, she revealed that she had lost 10 pounds in less than a month thanks to a combination of the medication and a new healthy lifestyle. "Two months ago, my doctor put me on, not Ozempic, Mounjaro, something like that…and [cholesterol medication] Repatha," she explained. "One I do every other week, the other I do once a week…I also really stopped drinking five or six Diet Cokes a day…And my appetite has decreased significantly -- it's probably the meds. And I’m trying to move more. So you know all those things combined, that's what it is."

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After followers noticed Khloé Kardashian’s extremely slim figure, rumors began to surface that she was Ozempic. Khloé finally fought back against the claims, clapping back in the comment section of her Instagram. "Let’s not discredit my years of working out. I get up 5 days a week at 6am to train. Please stop with your assumptions," she wrote. "I guess new year still means mean people."

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"Vanderpump Rules" star Katie Maloney says she isn't against the idea of using Ozempic. While discussing the trend of celebrities using the drug, she shared that she feels everyone should do what they want with their own bodies. "I say everyone do what you want to do. Understand the risks, and if it's right for you, it's right for you," she told People. "I think the expectations [for women to be thin] are always going be there whether or not there's like this miracle drug or not. The pressures are always going to be there. So thanks, Hollywood, thanks media, thanks society for keeping it going. But I just think, you know, if it makes you happy, follow your bliss."

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Lala Kent admits she feels differently about Ozempic than her "Vanderpump Rules" co-star. The reality star says that she's had "enough already" with people taking it for weight loss and believes it’s time for them to stop. "I think that Hollywood is all sorts of f--ked up. We've got to do better," she told People. "I think there's a lot of things that need to change and it starts with us and there are times where I roll my eyes and say, 'F--king do better, all of us.' We all need to participate in becoming better examples for our children in the outside world."

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“Million Dollar Matchmaker” Patti Stanger says that people she knows across the country are all using Ozempic. She later revealed that she’s also using a weight loss injection. "I'm on the shot. I'm gonna tell you the truth. I went on semaglutide, which is the ingredient in Ozempic. I got the worst acid reflux. And I was not feeling good. So, I stopped three weeks in," she said on the "Behind the Velvet Rope" podcast, adding that she now takes Tirzepatide and experiences less symptoms.

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Shortly after Meghan McCain gave birth to her second child, she says friends "urged" her to take Ozempic to help drop the baby weight. She explains that she found the whole thing "horrifying, unfair and disturbing" and would never want to take something that other people needed to be healthy. "I was even offered a black market freebie by someone with 'extra shots at home.' ...Let me make one thing very clear. I'm not taking it. I refuse. There's a clear moral issue here. It's hard to take a drug because swimsuit season is around the corner, while others need it to stay alive. And how can this be healthy?" Meghan wrote in a column for the Daily Mail.

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Celebrity trainer Jillian Michaels says there are a lot of negatives to taking Ozempic and she's recently had to help several friends get off the drug. She explained that once someone stops taking it, the weight will come back, so it's not even worth it. "I have taken at least eight family friends' parents off of this drug. They [were] getting heart palpitations, they're nauseous, they feel like s--t," she told People. 'Once they get off of the drug, it does the rebound effect. So you're not gaining anything. You get off the drug in a year and go all the way back. You've not learned anything. You've not built any physical strength or endurance. You haven't learned how to eat healthy. The truth of the matter is, Ozempic has some pretty significant side effects. Do your homework on it. The results are not lasting, in very large part."

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Stars Who Have Spoken Out On Weight Loss Drug Trend In Hollywood

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