Anyone staying in to watch TV tonight won't have too many options -- because the ambitious, star studded Stand Up to Cancer fundraiser will be taking over all the major networks.
FOX, NBC, ABC, CBS, HBO, Showtime and E! will all air the event, a fundraiser for cancer research.
Cancer survivors Christina Applegate, Maura Tierney, Michael C. Hall, Elizabeth Edwards, "Survivor's" Ethan Zohn, Sofia Vergara and Lance Armstrong will all appear -- as well as Michael Douglas, who is currently battling throat cancer.
Lady Antebellum, Leona Lewis, Green Day's Billie Joe Armstrong, Stevie Wonder and Neil Diamond are all scheduled to perform.
Not near a TV, just check back here and watch below. The pre-show stars at 7:30pm ET.
For info on how you can donate to the cause, go here.