Us Weekly reports that the fashion designer, 41, is expecting her second child with hubby Rodger Berman.
The couple -- who tied the knot in 1996 -- welcomed their first child together, son Skyler, in March 2011. We bet the little cutie is thrilled to have a sibling!
We know the Bravo star loves dressing her baby boy up in the latest fashions, so now she'll have another little one to style soon enough.
"Oh my God, my husband laughs at me because I spend more time in his [Skyler's] closet in the morning than I do in my own. And, you know, it's incredibly fun. It's like having a live doll. And he loves it," Zoe gushed about Skyler to MSN's WonderWall in January.
We're hoping Rachel's has a little girl this time around -- her style will be "Bananas"! Click "Launch Gallery" above to see more expecting stars!