"People don't stop at size 12. It's an odd thing that you can't go shopping with your friends because your store is upstairs hidden by the tire section," she told the magazine, referring to her new collection. "There is just this weird thing about how we perceive women in this country. I would love to be a part of breaking that down."
The "Spy" star's designs -- which are currently sold in stores like Macy's, Nordstrom and Bloomingdale's -- features a variety of styles and pieces, ranging from size 4-28.
"It's pretty consuming…my problem is, I don't hand things off very well. I just figure if it has my name on it and I want to make people feel good about wearing it, I can't pass it off," she revealed.
We think the actress looks absolutely amazing and we're loving her holiday collection -- what do you think about Melissa's new campaign? Tell toofab in the comment section below and click "Launch Gallery" above to see more stars who've shed major lbs!