However, Madonna wasn't the only celebrity who commented on Miley's post.
"We love you Miley stay strong," rapper Juicy J wrote. Actress Selma Blair also chimed in. "You are wonderful," she commented.
Bella Thorne, who also never shies away from being vulnerable on Instagram, wrote, "I love this. So much from the heart. Takes a lot to say. I love every version of u. Perfection is imperfect and that's a fact."
YouTube star Tana Mongeau, also voiced her support for Miley, commenting on her Twitter posts, "I LOVE U QUEEN."
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In her lengthy message, above, Miley denied cheating on Liam during their marriage.
"I can accept that the life I've chosen means I must live completely open and transparent with my fans who I love, and the public, 100% of the time," she began. "What I cannot accept is being told I'm lying to cover up a crime I haven't committed. I have nothing to hide."
"Once Liam and I reconciled, I meant it, and I was committed," she continued. "There are NO secrets to uncover here. I've learned from every experience in my life. I'm not perfect, I don't want to be, it's boring. I've grown up in front of you, but the bottom line is, I HAVE GROWN UP."
"I can admit to a lot of things but I refuse to admit my marriage ended because of cheating," she added. "Liam and I have been together for a decade. I've said it before & it remains true, I love Liam and always will."
Not only did Miley discuss her relationship with Liam, who filed for divorce from Miley on Wednesday, but she also addressed her controversial past and spoke about everything from smoking weed to twerking to nudes.
The "Wrecking Ball" singer also revealed she was axed from the film "Hotel Transylvania" after she bought Liam a penis cake for his birthday.
"You can say I am a twerking, pot smoking , foul mouthed hillbilly but I am not a liar," Miley concluded in her post. "I am proud to say, I am simply in a different place from where I was when I was a younger."
Earlier this month, it was revealed the "Hannah Montana" alum and "Hunger Games" star split after less than a year of marriage.
"Liam and Miley have agreed to separate at this time," a rep for Cyrus told People in a statement. "Ever-evolving, changing as partners and individuals, they have decided this is what's best while they both focus on themselves and careers."
The statement continued, "They still remain dedicated parents to all of their animals they share while lovingly taking this time apart. Please respect their process and privacy."
One day before the world learned of the breakup, Miley, while on a girls trip to Italy, was spotted locking lips with long-time friend Kaitlynn Carter.
A few weeks later, on Wednesday, Liam filed for divorce from Miley citing "irreconcilable differences", per TMZ.