Doctors spent ten hours trying to revive the tot, named Diego, but he died on Friday.
According to police, the couple admitted suffocating the infant until he was unconscious. Investigators said Camacho told them Villa wasn't the father, and that they didn't want the baby.
"By the looks of the nurses, they did everything they could to try and revive that kid," Oxnard Police Sgt. Brandon Ordelheid told the Times. "I can tell you this is probably one of the worst things these detectives can go through, is something like this, but we're still trying to figure out what happened."
The couple were both arrested for felony assault on a child by means of force resulting in the child's death; bail was set at $1million for Camacho, and $5million for Villa.