With the fallout over Harvey Weinstein still looming large when they sat down for the magazine, the conversation mainly focused on sexism and harassment, but included some light-hearted and hilarious moments as well.
Here are the five most noteworthy bites:
J-Law's Blowback for Defending Herself Against Sexual Harassment
"I finally made the decision to stand up for myself and then I went to go to the bathroom at work and one of the producers stopped me and was like, 'You know we can hear you on the microphone; you've been really unruly.' Which was not true, but basically my job was threatened because the director said something f-cked up to me and I said, 'That's sick, you can't talk to me like that,' and then I was punished and I got afraid that I wasn't going to be hired again," Lawrence said. "I was called difficult and a nightmare."
"I think a lot of people aren't coming forward because they're afraid they're not going to work again," she added. "You need to be able to say, 'This is wrong,' and have somebody do something about it, instead of saying, 'Oh it's wrong? Well, you're fired.'"
Though many of the headlines are currently coming out Hollywood, Lawrence said it's indicative of a larger problem.
"The entertainment industry is kind of the stage on which you can see the inner workings of problems that are all over the world," Lawrence said. "If a flight attendant comes forward about a pilot, it doesn't end up in the news because nobody knows about it. That doesn't mean that there's less sexual abuse going on anywhere else in the world, in any other place of work. But fortunately, we're starting the conversation now."
"After 'Zero Dark Thirty,' I was sent a lot of scripts where it was a female protagonist, and they wouldn't do my deal until they knew who the male actor was because they needed to do his deal first and then see what was left over," she revealed.
Now, Chastain said she doesn't go for that anymore.
"From now on, if someone has something they're bringing to me, great, let's do my deal [now]," she added. "But also, if someone is showing up for three weeks of a two-month film, they're not getting paid more than me."
Lawrence said she went into her latest movie knowing that it wouldn't necessarily be loved.
"We'd start shooting something, and we'd be like, 'Well, this is going to go over really well in the center of America.' We would laugh about it, but nobody had any doubts about what we were doing," she said of the film, which was met with much criticism and savaged by general audiences.
"We spent three months meeting in a warehouse in Brooklyn talking over the themes of the movie. By the time we got [to the shoot], we were rock solid to the point that even when the movie came out and we have an F CinemaScore or something, like 63 percent [on Rotten Tomatoes], nobody is really surprised," she added. "We're just like, 'Well, yeah, we knew that when we were on set.' Every time you make a movie, you're like, 'I hope everyone likes it.' This is the first time I've made a movie where we knew not everybody is going to like it. I mean, people haaate it."
Why Allison Janney Was Happy to Have Old-Age Makeup
Janney said that she actually enjoyed playing an older woman in the upcoming Margot Robbie film 'I, Tonya' because she could actually focus her performance rather than her appearance on screen.
"I got to do this old-age makeup and I was like three hours in this makeup, and then I saw myself and I was like, 'Oh my God, this is fantastic. I don't have to worry about my jowls,'" Janney said.
The 57-year-old actress continued to explain that it was "freeing" to go to work everyday without worrying about looks. Lawrence added, "It's so hard because the first time I watch anything, I'm just watching my double chin and my acne, and I'm bloated."