"The man is an after school special waiting to happen," the late-night host says.
"If you can't read, you can't be president," the comedian said on his HBO late-night show "Real Time" Friday, then used a "Real Housewives" analogy to make his point.
"I know Donald Trump is a stable genius, but he handles a teleprompter about as well as 'The Real Housewives' handle wine," Maher said. "That's why it took him an hour-and-a-half to sound out the State of the Union Address. The man is an after school special waiting to happen."
Maher continued to explain how Trump will avoid reading at all costs by borrowing a line from "Fire and Fury" author Michael Wolff, who wrote, "If it was in print, it might as well not exist."
"And pretty sneaky of Wolff to put it where Trump would never see it -- in a book," Maher said.
Maher, however, did cut the president some slack since his interest in written words may be as American as apple pie.
"Illiteracy isn't Trump's shame; it's his bond with us, a sub-literate president for a sub-literate country, a country where the majority of adults get their news from Facebook and 24 percent of teenagers are almost constantly online -- mostly with James Franco. A quarter of Americans say they haven't read a book in the past year and the other three quarters are lying."