The talk show host put the reality star on blast on Thursday, even declaring she preferred her before she transitioned from Bruce.
"Bruce was sensitive. I really liked Bruce. Thoughtful and the whole bit. He seemed like the most level-headed person. I used to love when he'd come in the room, you know, air to the conversation," she said. "Caitlyn though seems to be selfish and self-absorbed."
"I get it, Bruce waited all of his life to become Caitlyn, and he did it in front of all of us which was a teachable moment for all of us... but there's no excuse for not attending your child's wedding."
On Monday's episode of "The Hills: New Beginnings", Brody admitted he was "really hurt" when his father skipped his Indonesia wedding to Kaitlynn Carter in June of last year.
"Honestly, it really did hurt and I would have loved to have had her there," he said. "But she had better things to do. Apparently."
According to Wendy, the excuse of Caitlyn's presence being too much of a distraction was not cutting it.
"All of you are equally famous. People are over what you've done and who you've become Caitlyn. People are over it. I mean this is a new day. People say, 'Hey Caitlyn,' then keep walking... nobody cares about taking pictures with you," she said.
"If Kim is there, and all those others are there. All of yous have the equal fame, and beauty, and fortune and stuff like that. So, Caitlyn you're really nothing special anymore dear. Just saying."
Wendy even weighed in on claims that Jenner was a better parent to her step-daughters Kylie and Kendall, than she was to her four biological children.
"Bruce was a great father seemingly to Kylie and Kendall, but Brody and his brother Burt?" she said, citing episodes of KUWTK in which they claimed Jenner "wasn't really around, he was not the best father when they were young."
"I guess he was out running all the time," she said. "You know, being Bruce Jenner, being a star, and was kind of neglectful to them growing up. He was a hands-on father for the two girls, Kendall and Kylie."