"You all know I’ve been on this journey for most of my life," shared Winfrey. "My highest weight was 237 pounds. I don't know if there's another public person whose weight struggle has been exploited as much as mine over the years."
Waiting for your permission to load the Instagram Media.
When the topic turned to weight loss drugs, such as Ozempic, Winfrey spoke about not having "willpower."
"One of the things that I've been so ashamed, shamed myself about and was shamed in the tabloids every week for about 25 years is not having the willpower," she said.
"I think that there is a distinction between mindset which we are now hearing, the brain tells you a certain thing about how you process food versus willpower."
"Shouldn't we all just be more accepting of whatever body you choose to be in? That should be your choice," she added.
"Even when I first started hearing about the weight loss drugs, at the same time I was going through knee surgery, and I felt, 'I've got to do this on my own.' Because if I take the drug, that's the easy way out."