Jennifer Aniston 'Not Heartbroken' After Justin Theroux Split and Offers Golden Alternative to 'Friends' Reboot

Her first question: "I want to start this interview off light. When are you getting back together with Brad [Pitt]? Did Justin [Theroux] ever wear your jeans? And when are the twins due?"

Of course, McNearney -- Jimmy Kimmel's wife and longtime friend of Aniston -- wasn't expecting a serious answer from her subject, who broke into laughter. "You're the only person who could start an interview like that and actually send me into hysterics, not hives," Aniston said in response.

The topic of tabloid scrutiny over her personal life came up numerous times throughout the interview though, after McNearney commended her for being "poised and balanced" through it all.

"There are definitely moments of not being balanced and poised, but I do that all in my own personal space," said Jen. "For the most part I can sit back and laugh at the ridiculous headlines because they have gotten more and more absurd. I guess they're feeding into some sort of need the public has, but I focus on my work, my friends, my animals, and how we can make the world a better place. That other stuff is junk food that needs to go back in its drawer."

So, what does everyone get wrong about her? That answer was easy, as the same stories filled tabloids after her high-profile splits from both Brad and Justin, throughout her relationships with both of them and while dating everyone in between.

"It's pretty crazy. The misconceptions are 'Jen can't keep a man,' and 'Jen refuses to have a baby because she's selfish and committed to her career,'" she responded. "Or that I'm sad and heartbroken. First, with all due respect, I'm not heartbroken. And second, those are reckless assumptions."

"No one knows what's going on behind closed doors. No one considers how sensitive that might be for my partner and me. They don't know what I've been through medically or emotionally," she continued. "There is a pressure on women to be mothers, and if they are not, then they're deemed damaged goods. Maybe my purpose on this planet isn't to procreate. Maybe I have other things I'm supposed to do?"

Aniston later went on to condemn the double standard between how the media covers male and female celebrities, calling out the "fair share of sexism" she's experienced throughout her career.

"Women are picked apart and pitted against one another based on looks and clothing and superficial stuff," she said. "When a couple breaks up in Hollywood, it's the woman who is scorned. The woman is left sad and alone. She's the failure. F that. When was the last time you read about a divorced, childless man referred to as a spinster?"

Towards the end of the interview McNearney was also asked the one question every "Friends" star has been asked since the show went off the air almost 14 years ago: Will they ever come back?

While it seems unlikely, we're so down for the alternative Aniston offered up instead.

"Courteney [Cox] and Lisa [Kudrow] and I talk about it. I fantasize about it. It really was the greatest job I ever had. I don't know what it would look like today, but you never know," she answered. "So many shows are being successfully rebooted. I know Matt LeBlanc doesn't want to be asked that question anymore. But maybe we could talk him into it. Or we just give it some time and then Lisa, Courteney, and I could reboot 'The Golden Girls' and spend our last years together on wicker furniture."

Make. This. Happen.

The September issue of InStyle hits newsstands on August 10.