OJ Simpson Dead at 76 After Battle with Cancer -- Marcia Clark, Kato Kaelin, Caitlyn Jenner React

His family confirmed the news via X on Thursday, writing, "On April 10th, our father, Orenthal James Simpson, succumbed to his battle with cancer. He was surrounded by his children and grandchildren. During this time of transition, his family asks that you please respect their wishes for privacy and grace."

In February, Simpson denied he was in hospice care for prostate cancer, but didn't address his diagnosis. In 2023, however, he did say he "caught cancer," without specifying what type. At the time, he said he went through chemotherapy.

After a very successful football career in the '70s, Simpson transitioned to acting -- starring in a number of Hertz commercials, as well as The Naked Gun films.

In 1994, he became infamous after he was accused of murdering his ex-wife Nicole Brown Simpson and her friend Ron Goldman. His trial was dubbed the "Trial of the Century", attracting major attention worldwide. Though he was found not guilty in the criminal trial, he was found guilty of wrongful death in a civil trial.

The trial was later dramatized numerous times in the years since, with a TV movie, documentaries and the FX series The People v. O.J. Simpson: American Crime Story.

He caused controversy by writing a book titled "If I Did It," which was never released. Later in life, he was found guilty of multiple felonies including kidnapping and robbery stemming from an incident in a Las Vegas hotel room in 2007. After serving 9 years behind bars, Simpson was released on October 1, 2017.

He was very active on social media in the years since his release; his last post to X came back in February, two days after denying he was in hospice care.

Simpson is survived by his five children.

Following his death, Caitlyn Jenner -- who was once married to Nicole Brown Simpson's best friend, Kris Jenner -- took to X to share her reaction, simply posting, "Good Riddance #OJSimpson."

Marcia Clark, who was lead prosecutor in Simpson's trial, released a statement to ET reading, ""I send my condolences to Mr. Simpson's family."

Kato Kaelin, who was a houseguest of Simpson's at the time of the murders, also shared a video online in which he shared his condolences to O.J.'s kids, sent "love and compassion" to Ron Goldman's father Fred and spoke of Nicole Brown Simpson -- saying, "May we always cherish her memories. Nicole was a beacon of light. May we never forget her."

"I feel that the system failed Nicole Brown Simpson and failed battered women everywhere," Gloria Allred, who once represented Nicole's family, told ABC News. "I don't mourn for O.J. Simpson. I do mourn for Nicole Brown Simpson and her family and they should be remembered."

Fred Goldman, meanwhile, said Simpson's death was "just further reminder of Ron being gone all these years." He added, "It's no great loss to the world. It's a further reminder of Ron's being gone."

Alan Dershowitz, who was part of Simpson's legal team, said the "great athlete" will leave behind "a mixed legacy," noting how the case "played an important role in exposing the racial divisions in America" but left many people thinking he was both guilty, while just as many felt he was innocent.

On The View, the women of the show reacted to the news moments after it broke -- sharing their memories of the trial. For Sunny Hostin, the "injustice" of Simpson getting acquitted was "one of the reasons I became a prosecutor" -- while Alyssa Farah Griffin said he hoped his death "gives some peace to the family of the victims."

Magic Johnson also posted about the news on X, writing, "Cookie and I are praying for O.J. Simpson’s children ... and his grandchildren following his passing. I know this is a difficult time."

Former football star Torrey Smith, meanwhile, called out media using photos of Simpson in court for their obits -- saying, "Regardless of what you may think about him he was innocent in court and has kids out here. Y'all have no respect."

Antonio Brown also showed some sympathy for Simpson himself, tweeting, "Damn RIP ... RIP to the Legend OJ."